Chronic Osteomyelitis in Children Treated With Antibiotic-Laden Cement: A Preliminary Report

Authors Information
Article Notes and Dates
To Cite : Canavese F, Khan A. Chronic Osteomyelitis in Children Treated With Antibiotic-Laden Cement: A Preliminary Report, J Orthop Spine Trauma. 2016 ;2(2):e5283. doi: 10.17795/jost-5283.
Abstract
1. Introduction
2. Case Presentation
3. Discussion
Footnote
References
  • 1. Samuel S, Ismavel R, Boopalan PR, Matthai T. Practical considerations in the making and use of high-dose antibiotic-loaded bone cement. Acta Orthop Belg. 2010; 76(4): 543-5[PubMed]
  • 2. Harik NS, Smeltzer MS. Management of acute hematogenous osteomyelitis in children. Expert Rev Anti Infect Ther. 2010; 8(2): 175-81[DOI][PubMed]
  • 3. Gutierrez K. Bone and joint infections in children. Pediatr Clin North Am. 2005; 52(3): 779-94[DOI][PubMed]
  • 4. Catalano-Pons C, Raymond J, Chalumeau M, Armengaud JB, Kalifa G, Gendrel D. Case 2: paediatric chronic osteomyelitis: report of two cases. Case 1 diagnosis: pulmonary TB complicated by pneumomediastinum. Case 2 diagnosis: osteomyelitis caused by actinomyces. Acta Paediatr. 2007; 96(12): 1849-52[DOI][PubMed]
  • 5. Bar-On E, Weigl DM, Bor N, Becker T, Katz K, Mercado E, et al. Chronic osteomyelitis in children: treatment by intramedullary reaming and antibiotic-impregnated cement rods. J Pediatr Orthop. 2010; 30(5): 508-13[DOI][PubMed]
  • 6. Matzkin EG, Dabbs DN, Fillman RR, Kyono WT, Yandow SM. Chronic osteomyelitis in children: Shriners Hospital Honolulu experience. J Pediatr Orthop B. 2005; 14(5): 362-6[PubMed]
  • 7. Karger C, Kishi T, Schneider L, Fitoussi F, Masquelet AC, French Society of Orthopaedic S, et al. Treatment of posttraumatic bone defects by the induced membrane technique. Orthop Traumatol Surg Res. 2012; 98(1): 97-102[DOI][PubMed]
  • 8. Olesen UK, Eckardt H, Bosemark P, Paulsen AW, Dahl B, Hede A. The Masquelet technique of induced membrane for healing of bone defects. A review of 8 cases. Injury. 2015; 46 Suppl 8: 44-7[DOI][PubMed]
  • 9. Auh JS, Binns HJ, Katz BZ. Retrospective assessment of subacute or chronic osteomyelitis in children and young adults. Clin Pediatr (Phila). 2004; 43(6): 549-55[PubMed]
  • 10. Paley D, Herzenberg JE. Intramedullary infections treated with antibiotic cement rods: preliminary results in nine cases. J Orthop Trauma. 2002; 16(10): 723-9[PubMed]
  • 11. Zalavras CG, Patzakis MJ, Holtom P. Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin Orthop Relat Res. 2004; (427): 86-93[PubMed]
  • 12. Buchholz HW, Engelbrecht H. [Depot effects of various antibiotics mixed with Palacos resins]. Chirurg. 1970; 41(11): 511-5[PubMed]
  • 13. Buchholz HW, Gartmann HD. [Infection prevention and surgical management of deep insidious infection in total endoprosthesis]. Chirurg. 1972; 43(10): 446-53[PubMed]
  • 14. Wahlig H, Buchholz HW. [Experimental and clinical studies on the release of gentamicin from bone cement]. Chirurg. 1972; 43(10): 441-5[PubMed]
  • 15. Springer BD, Lee GC, Osmon D, Haidukewych GJ, Hanssen AD, Jacofsky DJ. Systemic safety of high-dose antibiotic-loaded cement spacers after resection of an infected total knee arthroplasty. Clin Orthop Relat Res. 2004; (427): 47-51[PubMed]
  • 16. Dovas S, Liakopoulos V, Papatheodorou L, Chronopoulou I, Papavasiliou V, Atmatzidis E, et al. Acute renal failure after antibiotic-impregnated bone cement treatment of an infected total knee arthroplasty. Clin Nephrol. 2008; 69(3): 207-12[PubMed]
  • 17. van Raaij TM, Visser LE, Vulto AG, Verhaar JA. Acute renal failure after local gentamicin treatment in an infected total knee arthroplasty. J Arthroplasty. 2002; 17(7): 948-50[PubMed]
  • 18. Curtis JM, Sternhagen V, Batts D. Acute renal failure after placement of tobramycin-impregnated bone cement in an infected total knee arthroplasty. Pharmacotherapy. 2005; 25(6): 876-80[PubMed]
  • 19. Cho SH, Song HR, Koo KH, Jeong ST, Park YJ. Antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis. Bull Hosp Jt Dis. 1997; 56(3): 140-4[PubMed]
  • 20. Walenkamp GH, Kleijn LL, de Leeuw M. Osteomyelitis treated with gentamicin-PMMA beads: 100 patients followed for 1-12 years. Acta Orthop Scand. 1998; 69(5): 518-22[PubMed]
  • 21. Cierny G3, Mader JT, Penninck JJ. A clinical staging system for adult osteomyelitis. Clin Orthop Relat Res. 2003; (414): 7-24[DOI][PubMed]
  • 22. Bassey LO, Antia-Obong OE, Antia UE. Sequestrectomy and local muscle flap implantation for chronic osteomyelitis in children and adolescents. East Afr Med J. 1995; 72(12): 787-90[PubMed]
  • 23. Hoang NT, Staudenmaier R, Feucht A, Hoehnke C. Effectiveness of free gracilis muscle flaps in the treatment of chronic osteomyelitis with purulent fistulas at the distal third of the tibia in children. J Pediatr Orthop. 2009; 29(3): 305-11[DOI][PubMed]
  • 24. Masquelet AC, Fitoussi F, Begue T, Muller GP. [Reconstruction of the long bones by the induced membrane and spongy autograft]. Ann Chir Plast Esthet. 2000; 45(3): 346-53[PubMed]
  • 25. Hollmig ST, Copley LA, Browne RH, Grande LM, Wilson PL. Deep venous thrombosis associated with osteomyelitis in children. J Bone Joint Surg Am. 2007; 89(7): 1517-23[DOI][PubMed]
  • 26. Nourse C, Starr M, Munckhof W. Community-acquired methicillin-resistant Staphylococcus aureus causes severe disseminated infection and deep venous thrombosis in children: literature review and recommendations for management. J Paediatr Child Health. 2007; 43(10): 656-61[DOI][PubMed]
  • 27. Bouchoucha S, Benghachame F, Trifa M, Saied W, Douira W, Nessib MN, et al. Deep venous thrombosis associated with acute hematogenous osteomyelitis in children. Orthop Traumatol Surg Res. 2010; 96(8): 890-3[DOI][PubMed]
  • 28. Wong TM, Lau TW, Li X, Fang C, Yeung K, Leung F. Masquelet technique for treatment of posttraumatic bone defects. ScientificWorldJournal. 2014; 2014: 710302[DOI][PubMed]
  • 29. Chadayammuri V, Hake M, Mauffrey C. Innovative strategies for the management of long bone infection: a review of the Masquelet technique. Patient Saf Surg. 2015; 9: 32[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Cited By:

Journal of Orthopedic and Spine Trauma accepts terms & conditions of:

International Committee of Medical Journal Editors (ICMJE) Citedby Linking DOI enabled Crossref iThenticate COPE Cross Check